Publications

Year 2017

The α-arrestin Bul1p mediates lactate transporter endocytosis in response to alkalinization and distinct physiological signals.
Talaia G, Gournas C, Saliba E, Barata-Antunes C, Casal M, André B, Diallinas G, Paiva S.
J Mol Biol. 2017 Sep 28. pii: S0022-2836(17)30451-5

Transition of yeast Can1 transporter to the inward-facing state unveils an α-arrestin target sequence promoting its ubiquitylation and endocytosis.
Gournas C, Saliba E, Krammer EM, Barthelemy C, Prévost M, André B.
Molecular Biology of the Cell. 2017 Oct 15;28(21):2819-2832

Year 2016

Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic Residues.
Krammer EM, Ghaddar K, André B, Prévost M.
PLoS One 11(8) (2016), e0160219

Function and Regulation of Fungal Amino Acid Transporters: Insights from Predicted Structure.
Gournas C, Prévost M, Krammer EM, André B.
Advances in Experimental Medicine and Biology 892 (2016), 69-106.

Year 2015

The AP-3 adaptor complex mediates sorting of yeast and mammalian PQ-loop-family basic amino acid transporters to the vacuolar/lysosomal membrane.
Llinares E, Barry AO, André B.
Scientific Reports 5 (2015), 16665

Year 2014

Substrate-induced ubiquitylation and endocytosis of yeast amino acid permeases.
Ghaddar K, Merhi A, Saliba E, Krammer EM, Prévost M, André B.
Molecular and Cellular Biology 34 (2014), 4447-4453.

Stress Conditions Promote Yeast Gap1 Permease Ubiquitylation and Downregulation via the Arrestin-like Bul and Aly Proteins.
Crapeau M, Merhi A, André B.
The Journal of Biological Chemistry 289 (2014), 22103-22116.

Converting the yeast arginine Can1 permease to a lysine permease.
Ghaddar K(#), Krammer EM(#), Mihajlovic N, Brohée S, André B(*), Prévost M(*).
(*) : last co-authors ; (#) first co-authors
The Journal of Biological Chemistry 289 (2014), 7232-7246

Year 2013

Nitrogen catabolite repressible GAP1 promoter, a new tool for efficient recombinant protein production in S. cerevisiae.
Debailleul F, Trubbia C, Frederickx N, Lauwers E, Merhi A, Ruysschaert JM, André B, Govaerts C.
Microbial Cell Factories 12 (2013), 129

Year 2012

Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy
Jézégou A, Llinares E, Anne C, Kieffer-Jaquinod S,  O’Regan S, Aupetit J, Chabli A, Sagné C, Debacker C, Chadefaux-Vekemans B, Journet A, André B, Gasnier B
PNAS 109 (2012), 3434-3443

Internal amino acids promote Gap1 permease ubiquitylation via TORC1/Npr1/14-3-3-dependent control of the Bul arrestin-like adaptors
Merhi A, André B.
Molecular and Cellular Biology 32 (2012), 4510-4522.

Year 2011

Unraveling networks of co-regulated genes on the sole basis of genome sequences.
Brohée S, Janky R, Abdel-Sater F, Vanderstocken G, André B, van Helden J.
Nucleic Acids Research 39(15) (2011), 6340-6358

Amino acid signalling in yeast: activation of Ssy5 protease is associated with its phosphorylation-induced ubiquitylation
Abdel-Sater F, Jean C, Merhi A, Vissers S & André B
Journal of Biological Chemistry 286 (2011), 12006-12015

Systematic mutational analysis of the intracellular regions of yeast Gap1 permease.
Merhi A, Gérard N, Lauwers E, Prévost M, André B (2011)
PLoS One 6(4):e18457

Year 2010

YTPdb: A wiki database of yeast membrane transporters
Brohée S, Barriot R, Moreau Y, André B
BBA Biomembranes 1798 (2010), 1908-1912

The Ubiquitin code of yeast permease trafficking
Lauwers E, Erpapazoglou Z, Haguenauer-Tsapis R, André B
Trends In Cell Biology 20 (2010), 196-204

Amino acid signalling in yeast: post-genome-duplication divergence of the Stp1 and Stp2 transcription factors
Wielemans K, Jean C, Vissers S, André B
Journal of Biological Chemistry 285 (2010), 855-865

Year 2009

K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway
Lauwers E, Jacob C, André B.
Journal of Cell Biology 185 (2009), 493-502

Gaussian Graphical Models to Infer Putative Genes Involved in Nitrogen Catabolite Repression in S. cerevisiae
Kontos K,  André B, van Helden J, Bontempi G
Lecture notes in computer science 5483 (2009), 13-24

 

Year 2008

Distinct transport mechanisms in yeast ammonium transport/sensor proteins of the mep/amt/rh family and impact on filamentation
Boeckstaens M, André B, Marini AM.
Journal of Biological Chemistry 283 (2008), 21362-21370

Machine learning techniques to identify putative genes involved in nitrogen catabolite repression in the yeast Saccharomyces cerevisiae
Kontos K, Godard P, André B, van Helden J, Bontempi G.
BMC proceedings 17;2 (2008) Suppl 4:S5.

Year 2007

Evidence for coupled Biogenesis of yeast Gap1 permease and sphingolipids: essential role in transport activity and normal control by ubiquitination
Lauwers E, Grossmann, André B
Molecular Biology of the Cell 18 (2007), 3068-3080

The split-ubiquitin two-hybrid assay to analyze protein-protein interactions at the endosome: application to yeast Bro1 interacting with ESCRT complexes, the Doa4 ubiquitin hydrolase and the Rsp5 ubiquitin ligase
Nikko E, André B
Eukaryotic Cell 6 (2007), 1266-1277

The yeast ammonium transport protein Mep2 and its positive regulator, the Npr1 kinase, play an important role in normal and pseudohyphal growth on various nitrogen media through retrieval of excreted ammonium
Boeckstaens M, Andre B, Marini AM
Molecular Microbiology 64 (2007), 534-546

Effect of 21 nitrogen sources on the global gene expression in the yeast Saccharomyces cerevisiae
Godard P, Urrestarazu A, Vissers S, Kontos K, Bontempi G, van Helden J, André B
Molecular and Cellular Biology 27 (2007), 3065-3086

Evidence for a direct role of the Doa4 deubiquitinating enzyme in protein sorting into the MVB pathway
Nikko E, André B
Traffic 8 (2007), 566-581

Year 2006

Rhophilin-2 is targeted to late-endosomal structures of the vesicular machinery in the presence of activated RhoB
Steuve I, Devosse T, Lauwers E, Vanderwinden JM, André B, Vourtoy P, Pirson I
Experimental Cell Research 312 (2006), 3981-3989

Transduction of the Nitrogen Signal Activating Gln3-mediated Transcription Is Independent of Npr1 Kinase and Rsp5-Bul1/2 Ubiquitin Ligase in Saccharomyces cerevisiae
Feller A, Boeckstaens M, Marini AM, Dubois E
The Journal of Biological Chemistry 281 (2006), 28546-28554

Association of yeast transporters with detergent-resistant membranes correlates with their cell-surface location
Lauwers E, Andre B
Traffic 7 (2006), 1045-1059

Structural involvement in substrate recognition of an essential aspartate residue conserved in Mep/Amt and Rh-type ammonium transporters
Marini AM, Boeckstaens M, Benjelloun F, Cherif-Zahar B, Andre B.
Current Genetics 49 (2006), 364-374

Physiological role of the putative ammonium transporter RhCG in the mouse
Biver S, Scohy S, Szpirer J, Szpirer C, Andre B, Marini AM .
Transfusion clinique et biologique 13 (2006), 167-168

From yeast ammonium transporters to Rhesus proteins, isolation and functional characterization
Marini AM, Boeckstaens M, Andre B.
Transfusion clinique et biologique 13 (2006), 95-96

Year 2005

CYGD: the Comprehensive Yeast Genome Database
Güldener U, Münsterkötter M, Kastenmüller G, Strack N, van Helden J, Lemer C, Richelles J, Wodak SJ, García-Martínez J, Pérez-Ortín JE, Michael H, Kaps A, Talla E, Dujon B, André B, Souciet J-L, De Montigny J, Bon E, Gaillardin C, Mewes HW
Nucleic Acids Research 33 (2005), D364-D368

Year 2004

Yeast Aqr1 is an internal membrane transporter involved in excretion of amino acids
Velasco I, Tenreiro S, Calderon I, André B
Eucaryotic Cell 3 (2004), 1492-1503

Amino acid signalling in yeast: casein kinase I and the Ssy5 endoprotease are key determinants of endoproteolytic activation of the membrane-bound Stp1 transcription factor
Abdel-Sater F, El Bakkoury M, Viisers S, Urrestarazu A. André B
Molecular and Cellular Biology 22 (2004), 9771-9785

K+ channel interactions detected by a genetic system optimized for systematic studies of membrane protein interactions
Obrdlik P, El-Bakkoury M, Hamacher T, Cappellaro C, Vilarino C, Fleischer C, Ellerbrok H, Kamuzinzi R, Ledent V, Blaudez D, Sanders D, Revuelta JL, Boles E, André B, Frommer WB
Proc Natl Acad Sci USA 101 (2004), 12242-12247

The external amino acid signalling pathway promotes activation of Stp1 and Uga35/Dal81 transcription factors for induction of the AGP1 gene in Saccharomyces cerevisiae
Abdel-Sater F, Iraqui I, Urrestarazu A. André B
Genetics 166 (2004), 1727-1739

Role of transporter like sensors in glucose and amino-acid signalling in yeast
Boles E, André B
Topics in Current Genetics 9 (2004), 121-153

Membrane trafficking of yeast transporters: mechanisms and physiological control of downregulation
Haguenauer-Tsapis R, André B
Topics in Current Genetics 9 (2004), 273-323

Year 2003

Molecular characterization, function and regulation of ammonium transporters (Amt) and ammonium-metabolizing enzymes (GS, NADP-GDH) in the ectomycorrhizal fungus Hebeloma cylindrosporum
Javelle A, Morel M, Rodriguez-Pastrana BR, Botton B, André B, Marini AM, Brun A, Chalot M
Molecular Microbiology 47 (2003), 411-430

High-affinity ammonium transporters and nitrogen sensing in mycorrhizas
Javelle A, André B, Marini AM, Chalot M
Trends Microbiology 11 (2003), 53-55

Homo- and hetero-oligomerization of ammonium transporter-1 NH4 uniporters
Ludewig U, Wilken S, Wu B, Jost W, Obrdlik P, El Bakkoury M, Marini A-M, André B, Hamacher T, Boles E, von Wiren N, Frommer WB.
Journal of Biological Chemistry 278 (2003), 45603-45610

Permease recycling and ubiquitination status reveal a particular role for Bro1 in the multivesicular body (MVB) pathway
Nikko E, Marini AM, André B
Journal of Biological Chemistry 278 (2003), 50732-50743

A novel gamma-hydroxybutyrate dehydrogenase: identification and expression of an Arabidopsis cDNA and potential role under oxygen deficiency
Breitkreuz KE, Allan WL, Van Cauwenberghe OR, Jakobs C, Talibi D, André B, and Shelp BJ
Journal of Biological Chemistry 278 (2003), 41552-41556

Year 2002

Functional profiling of the Saccharomyces cerevisiae genome
Giaever G, Chu AM, Ni L, Connelly C, Riles L, Veronneau S, Dow S, Lucau-Danila A, Anderson K, André B, Arkin AP, Astromoff A, El-Bakkoury M, Bangham R, Benito R, Brachat S, Campanaro S, Curtiss M, Davis K, Deutschbauer A, Entian KD, Flaherty P, Foury F, Garfinkel DJ, Gerstein M, Gotte D, Guldener U, Hegemann JH, Hempel S, Herman Z, Jaramillo DF, Kelly DE, Kelly SL, Kotter P, LaBonte D, Lamb DC, Lan N, Liang H, Liao H, Liu L, Luo C, Lussier M, Mao R, Menard P, Ooi SL, Revuelta JL, Roberts CJ, Rose M, Ross-Macdonald P, Scherens B, Schimmack G, Shafer B, Shoemaker DD, Sookhai-Mahadeo S, Storms RK, Strathern JN, Valle G, Voet M, Volckaert G, Wang CY, Ward TR, Wilhelmy J, Winzeler EA, Yang Y, Yen G, Youngman E, Yu K, Bussey H, Boeke JD, Snyder M, Philippsen P, Davis RW, Johnston M.
Nature 418 (2002), 387-391

Yeast Npi3/Bro1 is involved in ubiquitin-dependent control of permease trafficking
Springael J-Y, Nicco E, André B, Marini AM
FEBS Letters 517 (2002), 103-109

Year 2001

The Npr1 kinase controls biosynthetic and endocytic sorting of the yeast Gap1 permease
De Craene J-O, Soetens O, André B
Journal of Biological Chemistry 276 (2001), 43939-43948

Ubiquitin is required for sorting to the vacuole of the yeast Gap1 permease
Soetens O, De Craene J-O, André B
Journal of Biological Chemistry 276 (2001), 43949-43957

Molecular characterization of two ammonium transporters from the ectomycorrhiza fungus Hebeloma cylindrosporum
Javelle A, Rodriguez-Pastrana B-R, Jacob C, Botton B, Brun A, André B, Marini A-M, Chalot M
FEBS Letters 505 (2001), 393-398

The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane
Makuc J, Paiva S, Schauen M, Kramer R, Andre B, Casal M, Leao C, Boles E
Yeast 18 (2001), 1131-43

Genetic analysis of the signalling pathway activated by external amino acids in Saccharomyces cerevisiae
Bernard F, André B
Molecular Microbiology 41 (2001), 489-552

Ubiquitin and the SCFGrr1 ubiquitin ligase complex are involved in the signalling pathway activated by external amino acids in Saccharomyces cerevisiae
Bernard F, André B
FEBS Letters 496 (2001), 81-85

A genomic view of yeast membrane transporters
Van Belle D, André B
Current Opinion in Cell Biology 13 (2001), 389-396

Year 2000

The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast
Marini A-M, Matassi G, Raynal V, André B, Cartron J-P, Chérif-Zahar B
Nature Genetics 26 (2000), 341-344

In vivo-glycosylation of the Mep2 high-affinity ammonium transporter of Saccharomyces cerevisiae reveals a periplasmic NH2 terminus
Marini A-M, André B
Molecular Microbiology 38 (2000), 552-564

Cross-talk between NH4+ transporters in yeast and interference by the soybean SAT1 protein
Marini A-M, Springael J-Y, Frommer WB, André B
Molecular Microbiology 35 (2000), 378-385

A web site for the computational analysis of yeast regulatory sequences
Van Helden J, André B, Collado-Vides J
Yeast 16 (2000), 177-187

A new family of high-affinity transporters for adenine, cytosine, and purine derivatives in Arabidopsis
Gillissen B, Burkle L, André B, Kuhn C, Rentsch D, Brandl B, Frommer WB
Plant Cell 12 (2000) 291-300

Year 1999

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.
Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, André B, Bangham R, Benito R, Boeke JD, Bussey H,Chu AM, Connelly C, Davis K, Dietrich F, Dow SW, El Bakkoury M, Foury F, Friend SH, Gentalen E, Giaever G,Hegemann JH, Jones T, Laub M, Liao H, Davis RW, et al.
Science 285 (1999), 901-906

Amino acid signaling in Saccharomyces cerevisiae: a permease-like sensor of external amino acids and F-box protein Grr1p are required for transcriptional induction of the AGP1 gene, which encodes a broad-specificity amino acid permease
Iraqui I , Vissers S, Bernard F, De Craene J-O, Boles E , Urrestarazu A, André B
Molecular and Cellular Biology 19 (1999), 989-1001

A co-activator of nitrogen-regulated transcription in Saccharomyces cerevisiae
Soussi-Boudekou S, André B
Molecular Microbiology 31 (1999), 753-762

Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae
Iraqui I, Vissers S, André B, Urrestarazu A
Molecular and Cellular Biology 19 (1999), 3360-3371

NH4+-induced down-regulation of the Saccharomyces cerevisiae Gap1p permease involves its ubiquitination with lysine-63 linked chains
Springael J-Y, Galan J-M, Haguenauer-Tsapis R., André B
Journal of Cell Science 112 (1999), 1375-1383

The yeast Npi1/Rsp5 ubiquitin ligase lacking its N-terminal C2 domain is competent for ubiquitination but not for subsequent endocytosis of the Gap1 permease
Springael J-Y, De Craene J-O, André B
Biochemical and Biophysical Research Communications 257 (1999), 561-566

Year 1998

Nitrogen regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae
Springael J-Y, André B
Molecular Biology of the Cell 9 (1998), 1253-1263

Extracting regulatory sites from the upstream region of yeast genes by computational analysis of oligonucleeotide frequencies
van Helden J, André B, Collado-Vides J
Journal of Molecular Biology 281 (1998), 827-842

Amino acid transport in plants
Fisher W-N, André B, Rentsch D, Krolkiewuicz S, Tegeder M, Breitkreuz K, Frommer W
Trends in Plant Science 3 (1998), 188-195

Year 1997

A family of ammonium transporters in Saccharomyces cerevisiae
Marini A-M, Soussi-Boudekou S, Vissers S, André B
Molecular and Cellular Biology 17 (1997), 4282-4293

The Rh (Rhesus) blood group polypeptides are related to NH4+ transporters
Marini, A.-M., Urrestarazu, A., Beauwens, R. , André, B.
Trends in Biochemical Siences 22 (1997) , 460-461

Gzf3p, a fourth GATA factor involved in nitrogen-regulated transcription in
Saccharomyces cerevisiae
Soussi-Boudekou S, Vissers S, Urrestarazu A, Jauniaux J-C, André B
Molecular Microbiology 23 (1997): 1157-1168

A C-terminal di-leucine motif and nearby sequences are required for
NH4+ -induced inativation and degradation of the general amino-acid permease
(Gap1) of Saccharomyces cerevisiae
Hein C, André B
Molecular Microbiology 24 (1997): 607-616

The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its
evolutionaryi implications
Philippsen P, Kleine K, Pohlmann R, Dusterhoft A, Hamberg K, Hegemann JH, Obermaier B, Urrestarazu LA, Aert R, Albermann K, Altmann R, Andre B, Baladron V, Ballesta JP, Becam AM, Beinhauer J, Boskovic J, Buitrago MJ, Bussereau F, Coster F, Crouzet M, D’Angelo M, Dal Pero F, De Antoni A, Hani J, et al., including Vissers S and Iraqui Houssaini
Nature 387 (1997), 93-98

The nucleotide sequence of Saccharomyces cerevisiae chromosome XII
Johnston M, Hillier L, Riles L, Albermann K, Andre B, Ansorge W, Benes V, Bruckner M, Delius H, Dubois E, Dusterhoft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, Kotter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD, et al., including Urrestarazu LA and Vissers S
Nature 387 (1997), 87-90

The nucleotide sequence of chromosome IV from Saccharomyces cerevisiae
Jacq C, Alt-Morbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Blocker H, Blugeon C, Boskovic J, Brandt P, Bruckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, et al., including Urrestarazu LA and Vissers S
Nature 387 (1997), 75-78

The nucleotide sequence of yeast chromosome XVI
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S,Bruckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J, et al. , including Urrestarazu LA and Vissers S
Nature 387 (1997), 103-105

Year 1996

Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for
endocytosis of the yeast uracil permease
Galan J-M, Moreau V, André B, Volland C, Haguenauer-Tsapis R
The Journal of Biological Chemistry 271 (1996): 10946-10952

Year 1995

An overview of membrane transport proteins in Saccharomyces cerevisiae
André B
Yeast 11 (1995): 1575-1611

NPI1, an essential yeast protein involved in induced degradation of Gap1 and Fur4
permeases, encodes the Rsp5 ubiquitin-protein ligase
Hein C, Springael J-Y, Volland C, Hauguenauer-Tsapis R, André, B
Molecular Microbiology 18 (1995): 77-87

Cis- and trans-acting elements determining induction of the genes of the
4-aminobutyrate (GABA) utilization pathway in Saccharomyces cerevisiae
Talibi D, Grenson M and André B
Nucleic Acids Research 23 (1995), 550-557

Two mutually exclusive regulatory systems inhibit UAS(GATA) , a cluster of
5′-GAT(A/T)AT-3′ situated upstream from the UGA4 gene of
Saccharomyces cerevisiae
André B, Talibi D, Soussi Boudekou S, Hein C, Vissers S and Coornaert D
Nucleic Acids Research 23 (1995), 558-564

The yeast YBR235w gene encodes a homolog of the mammalian electroneutral
Na+-(K+)-Cl- cotransporter family
André B, Scherens, B
Biochemical and Biophysical Research Communications 205 (1995), 150-153