Novel study on the structural dynamics of an arginine transporter published

A novel collaborative study by Eva-Maria Krammer, Kassem Ghaddar, Bruno André and Martine Prévost was just published in PLoS One. The article entitled “Unveiling the Mechanism of Arginine Transport through AdiC with Molecular Dynamics Simulations: The Guiding Role of Aromatic Residuesreports the data obtained by molecular dynamics simulation methods unraveling the molecular details of arginine transport through the bacterial AdiC transporter. Have a look to the movie illustrating the molecular dynamics of the AdiC transporter. The conformational changes adopted by a transporter during transport catalysis are of high interest also in the context of yeast and human cells as they are thought to promote interactions with cytosolic factors involved in ubiquitylation and signaling.

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