Céline Barthélemy received her PhD diploma

On July 1rst, Céline Barthélemy publicly presented her PhD work and successfully received her diploma. Her research dealt with the mechanisms promoting endocytosis of the human LAT1 amino acid transporter in HeLa cancer cells. Céline could show that LAT1 endocytosis is triggered by ubiquitylation of the transporter via the Nedd4-2 ubiquitin ligase enzyme. She also investigated the influence of FTY720, an immunosuppressant compound, and found that it also provokes the endocytosis of LAT1, and of several amino acid permeases in yeast.